In vitro fertilization (IVF) is a complex procedure that helps to treat infertility. During this procedure, the eggs are retrieved from the woman’s uterus and fertilized with the sperm. The fertilized eggs known as the embryos are put in the incubator for a few days to allow it to grow. Then Dr Pai transfers around 1 to 2 embryos to the woman’s uterus. Pregnancy is confirmed if the embryo implants in the uterus lining. Dr. Hrishikesh Pai is one of the most successful and experienced fertility specialists in Mumbai.

Intracytoplasmic Sperm Injection (ICSI) is an advanced form of IVF wherein a single sperm is directly injected into the egg. It is usually used in case of male infertility or if previous IVF cycles have failed. Dr. Hrishikesh Pai recommends this treatment to patients who have surgically retrieved the sperms from the testes. The ICSI cycle is the same as a conventional IVF cycle. The only difference is that the best sperm is taken and is carefully injected into the egg with the help of a fine needle. This process is carried out under a powerful microscope and needs a high level of experience. Due to this reason, ICSI is more expensive than IVF charges in Mumbai.

Intrauterine insemination (IUI) is a commonly used fertility treatment. Generally, it is recommended when there is an issue of low sperm count or poor mobility. It may also be used in cases of unexplained infertility or if there is a cervical condition that prevents pregnancy. During IUI treatment, the sperms are first washed and concentrated and then placed directly into the woman’s uterus. It increases the chances of conception. The whole process is done within a few minutes and is relatively painless.

Intracytoplasmic morphologically sperm injection (IMSI) is an advanced technique that helps the embryologist to examine and select healthier sperm using a high-magnification digital imaging microscope. It helps to separate abnormal and impaired sperms that hinder the chances of pregnancy. IMSI technique provides magnification up to 6600 times which helps the embryologist to identify healthier sperms for ICSI. Dr. Hrishikesh Pai’s clinic was the first in India to install this technology.

Frozen embryo transfer (FET) is a process where the frozen embryos from your previous IVF cycle are thawed and transferred to your uterus. Mostly, the extra embryos from your IVF cycles are frozen for later use. Further, FET is gaining popularity for its success rate as well as for its pricing. This treatment cost is comparatively lesser than IVF charges in Mumbai as you will not need hormone stimulation medications and the egg retrieval process.

Dr. Hrishikesh Pai is the one who pioneered laser-assisted hatching (LAH) in India. This advanced technology increases implantation rates. Generally, laser-assisted hatching is done for all the case in their clinic. It is highly beneficial for cases of previous IVF failure, women who are above 37 years or for couples who are undergoing the FET cycle. The zona pellucid, which is the embryos’ outer wall becomes thick and difficult to hatch. With laser-assisted hatching, they soften the zona pellucid so that it can easily hatch and attach itself to the uterus.

When a couple cannot conceive due to issues in the male partner, it is called male factor infertility. The fertility issue may be related to poor sperm mobility, low sperm count, abnormal morphology, azoospermia, retrograde ejaculation, obstruction, illness, etc. Dr Hrishikesh Pai, with his years of experience, is an expert in helping couples with male fertility issues conceive. He offers various treatments such as TESA, PESA, TESE, Micro-TESE. Also, for people with male fertility, he prefers doing ICSI using IMSI technique as the best sperm can be selected, thereby increasing the chances of fertilization.

Preimplantation genetic testing (PGT) is a process where the blastocyst is genetically analysed for disorders such as thalassemia, Down’s syndrome, and sickle cell anemia. Dr. Hrishikesh Pai’s clinic is fitted with in-house genetic testing using S5 Ian Torrent Next-Generation Sequencing. With this method, Dr. Pai has helped a few patients of thalassemia and sickle cell anemia have normal babies. The test results take around 1 to 2 months to come. After around two months the frozen blastocysts which are genetically normal are transferred to the uterus.

Dr. Hrishikesh Pai encourages patients to undergo IVF using their own eggs. It may become a little difficult for women above 37 years as the quality and quantity of their eggs decreases. But with Dr. Pai’s experience and advancement in fertility treatment, it is possible. Latest fertility treatments such as ICSI, Assisted-Laser Hatching, PGT, Blastocyst Culture, Spindle Check, etc. helps older patients achieve pregnancy with their own eggs.