ICSI Treatment in India

Are you struggling with male-factor infertility?

Visit Bloom IVF Clinic to regain hope and happiness with ICSI treatment in India. Explore advanced fertility solutions, expert care, and a compassionate journey toward parenthood.

The desire to embrace parenthood, a journey of unconditional love, resonates deep within our hearts. However, for some, the path to conception may be challenging. Male infertility, a deeply sensitive and often overlooked issue, affects millions worldwide. It can lead to profound emotional distress for men and their partners, hampering their dreams of parenthood.

This is where the remarkable technique of Intra-Cytoplasmic Sperm Injection (ICSI) comes into play, offering a beacon of hope when hope seems faint. This revolutionary advanced IVF (In vitro fertilization) procedure involves delicately injecting a single sperm into the egg, bypassing the natural barriers that hinder fertilization.

ICSI Treatment in India

“ICSI is a marvel of modern science and stands at the forefront of assisted reproductive technologies (ART),” explains fertility expert Dr. Hrishikesh Pai. “In cases where conventional fertility treatments fall short, ICSI takes centre stage, empowering countless couples to overcome male infertility factors.”

Dr. Hrishikesh Pai was one of the first fertility specialists to perform ICSI Treatment in India in 1995, a procedure he has mastered over the years. He founded Bloom IVF Centre in India, a growing chain of world-class fertility clinics with compassionate experts, to provide a ray of hope for people struggling with fertility issues.


ICSI Treatment Procedure

Let us look at the step-by-step ICSI treatment procedure:

  1. Ovarian Stimulation: The first step in the ICSI procedure is to stimulate the ovaries using hormonal medications. It starts on the 2nd or 3rd day of the woman’s period and lasts 10 to 12 days. This encourages the development of multiple mature eggs, increasing the chances of successful fertilization.
  2. Sperm Collection: On the day of egg retrieval, a sperm sample is collected from the male partner or a sperm donor. If the male partner has fertility issues, the doctor can retrieve sperm surgically through procedures like Testicular Sperm Aspiration (TESA) or Micro TESE (Microdissection testicular sperm extraction).
  3. ICSI Treatment Procedure: After collection, the semen undergoes a 30-minute liquefaction period. Following this, healthy and motile sperm are separated from seminal fluid, immobile sperm, and other debris.
  4. Fertilization Check: The eggs are incubated overnight. The next day, the embryologist checks for signs of fertilization by examining the eggs for the presence of two pronuclei, indicating successful fertilization.
  5. Pregnancy Test: Around 2 weeks later, a pregnancy test is conducted to determine the success of the ICSI treatment. If the procedure is successful, the pregnancy progresses like a natural conception. ICSI is a remarkable assisted reproductive technology (ART) that requires a compassionate approach and the expertise of skilled professionals like Dr. Hrishikesh Pai. Dr. Pai, often called the best IVF Doctor in India, has enabled many couples to overcome male infertility and fulfil their dreams of becoming parents.
  6. Monitoring and Follicle Aspiration: The IVF team closely monitors the progress of ovarian stimulation using ultrasound scans and hormonal tests. Once the eggs are deemed mature, the doctor administers a trigger shot to stimulate ovulation. About 36 hours later, a minor surgical procedure called follicle aspiration or egg retrieval is performed. A thin needle is guided through the vaginal wall to extract the eggs from the ovaries under anesthesia.
  7. Embryo Culture and Transfer: Fertilized eggs (embryos) are cultured in a controlled laboratory environment for 5-6 days to reach the blastocyst stage. The embryologist monitors their development and selects the most viable embryos for transfer. The transfer procedure is typically painless and involves placing a thin catheter through the cervix to deposit the embryos in the uterine cavity.
  8. Egg Selection and Sperm Injection: The embryologist selects the best quality eggs under a high-powered microscope. Each mature egg is then stabilized using a holding pipette. At the same time, a delicate, hollow needle called the microinjection pipette injects a single sperm directly into the egg’s cytoplasm.


ICSI treatment cost in India

The ICSI cost in India can vary depending on various factors such as:

  • the location of the clinic
  • the reputation of the clinic
  • the expertise of the medical professionals involved
  • the facilities provided
  • the specific requirements of the individual’s case

The ICSI procedure cost in India can also vary based on additional procedures or treatments needed for the overall IVF treatment.

Please consult Dr. Hrishikesh Pai, the best IVF specialist in India, for an in-depth discussion to understand your goals and get up-to-date pricing information for the overall package.


The right candidate for ICSI treatment

The following are some scenarios to consider for ICSI treatment:

  • Incompetent Sperm: When faced with male infertility (low sperm count, poor sperm motility, or abnormal sperm morphology), ICSI can help by selecting the best sperm for fertilization.
  • Previous Fertilization Failure: ICSI can improve fertilization rates for couples with repeated IVF failures .
  • Azoospermia: ICSI can be beneficial when the male partner has obstructive href=”https://www.drhrishikeshpai.com/services/azoospermia-treatment-in-india/”> azoospermia (a condition where sperm is produced but not ejaculated) or non-obstructive azoospermia (where sperm production is impaired).
  • Presence of Antisperm Antibodies: In some cases, the female partner’s immune system may produce antibodies against the sperm, hindering fertilization. ICSI can bypass this issue.
  • Frozen Sperm Samples: ICSI can be used when using frozen sperm samples, as they may have reduced motility, and the direct injection of sperm increases the chances of successful fertilization.

Please consult qualified fertility specialist Dr. Hrishikesh Pai to undergo a comprehensive fertility evaluation and determine whether ICSI is the right treatment option for you.


ICSI success rate in India by age

Following are some approximate figures of the ICSI success rate by age of the female partner:

  • Women Under 35: 50% to 60% per cycle.
  • Women Between 35 and 37: 45% to 55% per cycle.
  • Women Between 38 and 40: 35% to 45% per cycle.
  • Women Over 40: 20% to 35% per cycle or even lower.

“The age of the female partner can influence the success rate of ICSI, as female fertility tends to decline with advancing age,” adds the highly-skilled IVF doctor in Mumbai, Dr. Hrishikesh Pai. “ Cryopreservation can be a great option for people planning on late parenthood to preserve their fertility.”

The live birth rate at our Bloom IVF clinic is around 40 to 50%, making Dr. Hrishikesh Pai among the leading IVF specialists in India.

Potential Risks

ICSI is generally a safe and effective fertility treatment, but like any medical procedure, it carries some risks, like:

  • OHSS: Medications used for ovarian stimulation in ICSI may lead to swollen and painful ovaries, requiring medical intervention.
  • Multiple Pregnancies: ICSI can lead to multiple embryos, increasing health risks for both the mother and babies.
  • Ectopic Pregnancy: ICSI carries a small risk of embryo implantation outside the uterus, necessitating immediate medical attention.
  • Birth Defects: ICSI is associated with a slightly increased risk of certain congenital disabilities.
  • Failed Fertilization: Despite advanced techniques, fertilization may not occur in some ICSI cases, requiring alternative options or additional cycles.

Post-operative Care after ICSI

  • Rest and Recovery: It is essential to take it easy and rest for a day or 2 to alleviate any discomfort.
  • Medications: Follow the prescribed medications and hormonal treatments directed by the fertility specialist to support the embryo implantation process.
  • Avoid Strenuous Activities: Avoid heavy lifting, strenuous exercise, or any activity that may stress the pelvic region for a few days after the procedure.
  • Follow-up Appointments: Attend all scheduled follow-up appointments with the fertility clinic to monitor progress and receive any necessary guidance or adjustments to the treatment plan.

Adhering to the prescribed post-operative guidelines can contribute to a smoother recovery and enhance the chances of a successful outcome,” advises fertility expert  Dr. Hrishikesh Pai. 


Seeking professional help and breaking the stigma surrounding male infertility is essential. Advanced treatments and support can offer hope and a pathway toward achieving the cherished gift of fatherhood. The journey through ICSI can help fulfil your most profound desire to have a child.

Where can you consult us?

Bloom IVF has clinics all over India for the convenience of the patients. We have more than nine IVF centres in India at  Mumbai, Delhi, Gurgaon, Faridabad, Mohali, Nagpur, KolkataLucknow, and Indore.


Frequently Asked Questions

How much does ICSI cost in India?

The cost of ICSI treatment in India varies from clinic to clinic. You must visit the clinic for a consultation to know the exact cost. We at Bloom IVF provide this procedure at an affordable price.

Is ICSI better than IVF?

According to research, IVF and ICSI are both effective procedures with the same live birth success rates. However, ICSI has a better fertilization rate of 80 to 85 percent.

Do you need complete bed rest after ICSI treatment?

Bed rest is not necessary. However, it is advisable not to over-exert yourself. Also, a stress-free, positive mind and a healthy diet can improve your chances of conceiving.

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