Sequential Embryo Transfer in Mumbai

Blastocyst transfer is a technique for improving IVF success in patients who have had many IVF failures. However, the quantity of fertilized oocytes and the quality of the fertilized embryos are factors that influence the outcome of this method.

As a result, the sequential transfer method provides the benefits of blastocyst transfer without exposing the entire cycle to the possibility of cancellation.

Growing embryos to the blastocyst stage will serve two purposes, assuming that embryos that stop developing in the womb fail to implant. It will allow for improved embryo selection for transfer, as well as higher physiologic synchronization with the endometrium and the ability to achieve the “implantation window.”

The transfer of blastocyst-stage embryos helps overcome the random selection of damaged embryos, and the possibility of multiple pregnancies is reduced.

IVF does not always result in embryos that survive to the blastocyst stage, which results in cycle cancellation. Therefore, this method is only appropriate for people who produce a large number of embryos.

The motive behind sequential embryo transfer is that the embryos (1 or 2 embryos) may promote an increase in endometrial receptivity during the first day-3 transfer, resulting in a better endometrial environment for the second day-5 transfer (1 blastocyst).

In this process, two sets of embryos are transferred to the mother’s womb in one cycle (on days 3 and 5), as previously mentioned.

• The first group consists of the quickest developing embryos implanted within three days after their formation.
• Once the initial batch is placed in the uterus, another set is transferred a few days later.
• The second group has proceeded to the blastocyst stage, which is more developed than the first.
• It helps boost the chances of conceiving.
• As they are more mature, the second batch is more likely to attach to the uterine lining.
• The first group produces hormones known as cytokines to enhance the uterus and increase successful implantation.
• We cryopreserve additional embryos for the future fertility cycle.

According to Dr. Hrishikesh Pai, one of the best IVF doctor in India, many couples opt for sequential embryo transfer in Mumbai for its many advantages, such as –

• A high rate of embryo implantation
• A high pregnancy rates
• An expected multiple pregnancy rate
• It helps prevent complications like blastocyst transfer cycle cancellation.